COVID-19 increases the risk of developing type 2 diabetes, research reveals

Studies have shown that the pancreas can also be a target for (a serious acute respiratory syndrome coronavirus type 2 virus). Decreased -secreting granules in beta cells and impaired glucose-stimulated insulin secretion have been observed following Covid-19 infection.

In addition, some patients developed insulin resistance after COVID-19 and had high blood sugar, even though they had no history of diabetes. SARS-CoV-2 infection can lead to a strong release of pro-inflammatory signaling agents (cytokines). Activation of the may continue for months after SARS-CoV-2 infection and impair the effectiveness of insulin (muscle, fat cells, liver).

So far, however, it has been unclear whether these metabolic changes are transient or whether Covid-19 increases the risk of persistent diabetes. To investigate this issue, researchers from the German Diabetes Center (DDZ), the German Diabetes Research Center (DZD), and IQVIA (Frankfurt) conducted a retrospective cohort study.

The cohort study included a representative panel of 1,171 physician clinics across (March 2020 to January 2021: 8.8 million patients). Monitoring continued until July 2021.

“The aim of our study was to investigate the incidence of diabetes after SARS-CoV-2 infection,” said the first author. Wolfgang RathmannDirector of the DDZ Epidemiology Research Group.

As a control group, the researchers chose people with acute upper respiratory tract infections (AURIs), which are also often caused by viruses. The two cohorts were compared based on , age, health insurance, month of Covid-19 or AURI diagnosis, and comorbidities (, hypertension, high cholesterol, heart attack, ). Patients treated with corticosteroids were excluded from the study.

Covid-19 was detected in 35,865 people during the study period.

“Our analyzes showed that Covid-19 patients developed type 2 diabetes more often than AURI patients. The incidence of diabetes caused by Covid-19 infection was 15.8 compared with 12.3 cases per 1000 AURI patients per year. Statistical analysis resulted in a Rath ratio ( The IRR) is 1.28. Simply put, this means that the relative risk of developing type 2 diabetes was 28 percent higher in the Covid-19 group than in the AURI group, “Rathmann summarized the results.

Although type 2 diabetes is unlikely to be a problem for most people with mild Covid-19 disease, the authors recommend that anyone who has recovered from Covid-19 disease be alert to warning signs and symptoms, such as , frequent urination. and increased thirst and seek immediate treatment.


# COVID-19

Source: The Nordic Page

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